Jose A. Chavez

GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

Shannon E. Mullican, Xiefan Lin‐Schmidt, Chen‐Ni Chin et al. · Nature Medicine · 2017 · 726 citations

Obesity, Metabolic Syndrome, Energy Homeostasis +12

A Role for Ceramide, but Not Diacylglycerol, in the Antagonism of Insulin Signal Transduction by Saturated Fatty Acids

Jose A. Chavez, Trina A. Knotts, Liping Wang et al. · Journal of Biological Chemistry · 2003 · 601 citations · Full text

A Ceramide-Centric View of Insulin Resistance

Jose A. Chavez, Scott A. Summers · Cell Metabolism · 2012 · 583 citations · Full text

Insulin Resistance, Metabolic Syndrome, Obesity +7

Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes

Jose A. Chavez, Scott A. Summers · Archives of Biochemistry and Biophysics · 2003 · 504 citations

Obesity, Saturated Fatty Acids, Insulin Signaling +11

Rab10, a Target of the AS160 Rab GAP, Is Required for Insulin-Stimulated Translocation of GLUT4 to the Adipocyte Plasma Membrane

Hiroyuki Sano, Lorena Eguez, Mary N. Teruel et al. · Cell Metabolism · 2007 · 371 citations · Full text

Signal Transduction, Molecular Physiology, Biochemistry +9