Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma

Manuel Fankhauser, Maria A.S. Broggi, Lambert Potin, +13

Science Translational Medicine

Lymph node stromal cells acquire peptide–MHCII complexes from dendritic cells and induce antigen-specific CD4+ T cell tolerance

Juan Dubrot, Fernanda V. Durães, Lambert Potin, +8

The Journal of Experimental Medicine

Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours

Aslan Mansurov, Jun Ishihara, Peyman Hosseinchi, +9

Nature Biomedical Engineering

InflammationCytokineCancer ImmunosurveillanceCold Mouse TumoursImmunology +8

Targeted antibody and cytokine cancer immunotherapies through collagen affinity

Jun Ishihara, Ako Ishihara, Koichi Sasaki, +15

Science Translational Medicine

Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events

Jun Ishihara, Kazuto Fukunaga, Ako Ishihara, +6

Science Translational Medicine

Recruitment of CD103 ⁺ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy

John‐Michael Williford, Jun Ishihara, Ako Ishihara, +6

Science Advances

Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients

Maria A.S. Broggi, Léa Maillat, Cristina C. Clement, +12

The Journal of Experimental Medicine

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity

Jun Ishihara, Ako Ishihara, Lambert Potin, +6

Molecular Cancer Therapeutics

The Number of Toll-Like Receptor 9-Agonist Motifs in the Adenovirus Genome Correlates with Induction of Dendritic Cell Maturation by Adenovirus Immune Complexes

Matthieu Perreau, Hugh C. Welles, Céline Pellaton, +10

Journal of Virology

Adenovirus Immune ComplexesAdaptive Immune SystemInnate Immune SystemImmunologyImmunotherapy +15

Pro-lymphangiogenic VEGFR-3 signaling modulates memory T cell responses in allergic airway inflammation

Katharina Maisel, Cara L. Hrusch, Jorge Emiliano Gomez Medellin, +8

Mucosal Immunology

AsthmaInflammationAllergyInflammatory Lung DiseaseLung Inflammation +9