Shin Kwak

RNA editing and death of motor neurons

Yukio Kawahara, Kyoko Ito, Hui Sun et al. · Nature · 2004 · 541 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Motor Neurons +6

Reduction of GluR2 RNA editing, a molecular change that increases calcium influx through AMPA receptors, selective in the spinal ventral gray of patients with amyotrophic lateral sclerosis

Hiroshi Takuma, Shin Kwak, Toshihiro Yoshizawa et al. · Annals of Neurology · 1999 · 202 citations

Neurodegenerative Diseases, Calcium Influx, Amyotrophic Lateral Sclerosis +13

A role for calpain-dependent cleavage of TDP-43 in amyotrophic lateral sclerosis pathology

Takenari Yamashita, Takuto Hideyama, Kosuke Hachiga et al. · Nature Communications · 2012 · 167 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Signal Transduction +9

Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2

Takuto Hideyama, Takenari Yamashita, Takeshi Suzuki et al. · Journal of Neuroscience · 2010 · 158 citations · Full text

Human spinal motoneurons express low relative abundance of GluR2 mRNA: an implication for excitotoxicity in ALS

Yukio Kawahara, Shin Kwak, Hui Sun et al. · Journal of Neurochemistry · 2003 · 122 citations

Low Relative Abundance, Ampa Receptor Subunits, Neurotransmission +16