Hiroshi Takuma

Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells

Naohiro Egawa, Shiho Kitaoka, Kayoko Tsukita et al. · Science Translational Medicine · 2012 · 562 citations

Life Sciences, Neurology, Neuroscience +12

A new amyloid β variant favoring oligomerization in Alzheimer's‐type dementia

Takami Tomiyama, Tetsu Nagata, Hiroyuki Shimada et al. · Annals of Neurology · 2008 · 424 citations

Life Sciences, Neurobiology, Neuroscience +17

A Mouse Model of Amyloid β Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss <i>In Vivo</i>

Takami Tomiyama, Shogo Matsuyama, Hiroyuki Iso et al. · Journal of Neuroscience · 2010 · 393 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

CpG Demethylation Enhances Alpha-Synuclein Expression and Affects the Pathogenesis of Parkinson's Disease

Lumine Matsumoto, Hiroshi Takuma, Akira Tamaoka et al. · PLoS ONE · 2010 · 309 citations · Full text

Life Sciences, Genetics, Neuroscience +17

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis

Keiko Imamura, Yuishin Izumi, Akira Watanabe et al. · Science Translational Medicine · 2017 · 256 citations · Full text

Life Sciences, Neurology, Neuroscience +13