Concepedia

John E. Knox

JE

33

Publications

1.8K

Citations

23

H-Index

1972

Active since

Affiliations

Revolution Medicines (United States)(Current)

Wayne State University

Novartis (Singapore)

Memorial Sloan Kettering Cancer Center

Harvard University

John E. Knox is an author at Revolution Medicines (United States) specializing in medicine, pharmacology, and drug discovery.

ORCID

Top concepts

Publications per year

1972–2025

33

Publications

33

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

Matthew Holderfield, Bianca J. Lee, Jingjing Jiang et al. · Nature · 2024 · 268 citations · Full text

Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers

Jingjing Jiang, Lingyan Jiang, Benjamin J. Maldonato et al. · Cancer Discovery · 2024 · 231 citations · Full text

Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS

Christopher J. Schulze, Kyle J. Seamon, Yulei Zhao et al. · Science · 2023 · 203 citations · Full text

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors

Zheng Yin, Sejal Patel, Weiling Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 152 citations · Full text

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Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis

Mekonnen Kurabachew, Shuihua Lu, Philipp Krastel et al. · Journal of Antimicrobial Chemotherapy · 2008 · 99 citations

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