John A. Grout

Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

Jérôme C. Martin, Christie Chang, Gilles Boschetti et al. · Cell · 2019 · 850 citations · Full text

Inflammation, Chronic Inflammatory Diseases, Anti-tnf Therapy +12

Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification

Andrew M. Leader, John A. Grout, Bárbara Maier et al. · Cancer Cell · 2021 · 333 citations · Full text

Cancer Detection, Tumor Heterogeneity, Medicine +13

Spatial Positioning and Matrix Programs of Cancer-Associated Fibroblasts Promote T-cell Exclusion in Human Lung Tumors

John A. Grout, Philémon Sirven, Andrew M. Leader et al. · Cancer Discovery · 2022 · 272 citations · Full text

TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer

Matthew D. Park, Ivan Reyes-Torres, Jessica LeBérichel et al. · Nature Immunology · 2023 · 204 citations · Full text

Lung Inflammation, Medicine, Immunology +8

BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology

Camille Bigenwald, Jessica Le Bérichel, C. Matthias Wilk et al. · Nature Medicine · 2021 · 76 citations · Full text

Cell Signaling, Histiocytosis Pathophysiology, Autophagy +6