Roberta Cascella

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers

Giuliana Fusco, Serene W. Chen, Philip T. F. Williamson et al. · Science · 2017 · 666 citations · Full text

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity

Michele Perni, Céline Galvagnion, Alexander S. Maltsev et al. · Proceedings of the National Academy of Sciences · 2017 · 289 citations · Full text

Proteinlipid Interaction, Neurodegenerative Diseases, Aggregation Process +11

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

Roberta Cascella, Serene W. Chen, Alessandra Bigi et al. · Nature Communications · 2021 · 221 citations · Full text

Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity

Benedetta Mannini, Estefania Mulvihill, Caterina Sgromo et al. · ACS Chemical Biology · 2014 · 205 citations

Proteinlipid Interaction, Oligomeric Species, Protein Assembly +20

Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers

Benedetta Mannini, Roberta Cascella, Mariagioia Zampagni et al. · Proceedings of the National Academy of Sciences · 2012 · 159 citations · Full text

Protein Chemistry, Aberrant Protein Oligomers, Protein Function +15