Serene W. Chen

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers

Giuliana Fusco, Serene W. Chen, Philip T. F. Williamson et al. · Science · 2017 · 666 citations · Full text

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation

Serene W. Chen, Srdja Drakulić, Emma Deas et al. · Proceedings of the National Academy of Sciences · 2015 · 459 citations · Full text

Amyloid Oligomers, Structural Characterization, Protein Assembly +17

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

Emma Deas, Nunilo Cremades, Plamena R. Angelova et al. · Antioxidants and Redox Signaling · 2015 · 352 citations · Full text

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity

Michele Perni, Céline Galvagnion, Alexander S. Maltsev et al. · Proceedings of the National Academy of Sciences · 2017 · 289 citations · Full text

Proteinlipid Interaction, Neurodegenerative Diseases, Aggregation Process +11

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

Roberta Cascella, Serene W. Chen, Alessandra Bigi et al. · Nature Communications · 2021 · 221 citations · Full text