Paola Ruzzenenti

Oversulfated heparins with low anticoagulant activity are strong and fast inhibitors of hepcidin expression in vitro and in vivo

Maura Poli, Michela Asperti, Paola Ruzzenenti et al. · Biochemical Pharmacology · 2014 · 48 citations

Medicine, Biochemistry, Pharmacology +11

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice

Maura Poli, Ferdous Anower-E-Khuda, Michela Asperti et al. · Journal of Biological Chemistry · 2019 · 26 citations · Full text

Medicine, Biochemistry, Cell Signaling +16

The Ferritin-Heavy-Polypeptide-Like-17 (FTHL17) gene encodes a ferritin with low stability and no ferroxidase activity and with a partial nuclear localization

Paola Ruzzenenti, Michela Asperti, Stefania Mitola et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2015 · 24 citations

Life Sciences, Genetics, Molecular Biology +4

High Sulfation and a High Molecular Weight Are Important for Anti-hepcidin Activity of Heparin

Michela Asperti, Annamaria Naggi, Emiliano Esposito et al. · Frontiers in Pharmacology · 2016 · 17 citations · Full text

Medicine, Biochemistry, Pharmacology +17

BMP6 binding to heparin and heparan sulfate is mediated by N-terminal and C-terminal clustered basic residues

Andrea Denardo, Stefano Elli, Stefania Federici et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2020 · 16 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10