NCOA4-mediated ferritinophagy promotes ferroptosis induced by erastin, but not by RSL3 in HeLa cells

Magdalena Gryzik, Michela Asperti, Andrea Denardo, +2

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Lipid PeroxidationAutophagyRedox BiologyHela CellsReactive Oxygen Specie +6

Cell growth potential drives ferroptosis susceptibility in rhabdomyosarcoma and myoblast cell lines

Silvia Codenotti, Maura Poli, Michela Asperti, +3

Journal of Cancer Research and Clinical Oncology

Myoblast Cell LinesCell DivisionCell InteractionMolecular BiologyCell Proliferation +5

Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo

Maura Poli, Michela Asperti, Annamaria Naggi, +9

Blood

H-ferritin suppression and pronounced mitochondrial respiration make Hepatocellular Carcinoma cells sensitive to RSL3-induced ferroptosis

Michela Asperti, Sonia Bellini, Elisabetta Grillo, +9

Free Radical Biology and Medicine

Hepatocellular Carcinoma CellsPathologyCell DeathRedox BiologyH-ferritin Suppression +14

Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity

Federica Maccarinelli, Elena Gammella, Michela Asperti, +12

Journal of Molecular Medicine

Oversulfated heparins with low anticoagulant activity are strong and fast inhibitors of hepcidin expression in vitro and in vivo

Maura Poli, Michela Asperti, Paola Ruzzenenti, +8

Biochemical Pharmacology

PharmacotherapyFast InhibitorsThrombosisHematologyHepatotoxicity +14

Sucrosomial® Iron Supplementation in Mice: Effects on Blood Parameters, Hepcidin, and Inflammation

Michela Asperti, Magdalena Gryzik, Elisa Brilli, +7

Nutrients

Caveolin-1 promotes radioresistance in rhabdomyosarcoma through increased oxidative stress protection and DNA repair

Silvia Codenotti, Francesco Marampon, Luca Triggiani, +11

Cancer Letters

Genome InstabilityCaveolin-1 Promotes RadioresistanceOncogenic AgentMolecular BiologyOxidative Stress Protection +5

Iron supplementation enhances RSL3-induced ferroptosis to treat naïve and prevent castration-resistant prostate cancer

Federica Maccarinelli, Daniela Coltrini, Silvia Mussi, +13

Cell Death Discovery

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice

Maura Poli, Ferdous Anower-E-Khuda, Michela Asperti, +6

Journal of Biological Chemistry