Oversulfated heparins with low anticoagulant activity are strong and fast inhibitors of hepcidin expression in vitro and in vivo

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Elizabeta Nemeth, Marie S. Tuttle, Julie Powelson et al. · Science · 2004 · 4.8K citations

Medicine, Cell Biology, Physiology +17

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

Jodie L. Babitt, Franklin W. Huang, Diedra M. Wrighting et al. · Nature Genetics · 2006 · 1K citations

Life Sciences, Cell Biology, Molecular Biology +10

STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation

Maria Vittoria Verga Falzacappa, Maja Vujić Spasić, Regina Kessler et al. · Blood · 2006 · 569 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

Laura Silvestri, Alessia Pagani, Antonella Nai et al. · Cell Metabolism · 2008 · 550 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Evidence for a 3-O-sulfated D-glucosamine residue in the antithrombin-binding sequence of heparin.

Ulf Lindahl, G. Bäckström, L Thunberg et al. · Proceedings of the National Academy of Sciences · 1980 · 489 citations · Full text

Life Sciences, Biochemistry, Carbohydrate Chemistry +16