Claude F. Purchase

A Rationalization of the Acidic pH Dependence for Stromelysin-1 (Matrix Metalloproteinase-3) Catalysis and Inhibition

Linda L. Johnson, A.G. Pavlovsky, Adam R. Johnson et al. · Journal of Biological Chemistry · 2000 · 75 citations · Full text

X‐ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: Implications for inhibitor selectivity

A.G. Pavlovsky, Mark Williams, Qi‐Zhuang Ye et al. · Protein Science · 1999 · 72 citations · Full text

X-ray Crystallography, Improved Mmp Inhibitors, Inhibitor Selectivity +18

Bioactivation and irreversible binding of the cognition activator tacrine using human and rat liver microsomal preparations. Species difference.

Thomas F. Woolf, W F Pool, Susan M. Bjorge et al. · Drug Metabolism and Disposition · 1993 · 62 citations

Inhibitors of Acyl-CoA:Cholesterol <i>O</i>-Acyltransferase. Synthesis and Pharmacological Activity of (±)-2-Dodecyl-α-phenyl-<i>N</i>-(2,4,6-trimethoxyphenyl)-2<i>H</i>-tetrazole-5-acetamide and Structurally Related Tetrazole Amide Derivatives

Patrick O’Brien, Drago R. Sliskovic, Joseph A. Picard et al. · Journal of Medicinal Chemistry · 1996 · 35 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Derivative (Chemistry) +14

Alkylation of Tetrazoles Using Mitsunobu Conditions

Claude F. Purchase, Andrew D. White · Synthetic Communications · 1996 · 22 citations

Asymmetric Catalysis, Chemical Engineering, Chiral Centers +10