Joseph A. Picard

Structure−Activity Relationships and Pharmacokinetic Analysis for a Series of Potent, Systemically Available Biphenylsulfonamide Matrix Metalloproteinase Inhibitors

Patrick O’Brien, Daniel F. Ortwine, A.G. Pavlovsky et al. · Journal of Medicinal Chemistry · 2000 · 97 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Effective Mmp Inhibitors +19

Inhibitors of Acyl-CoA:Cholesterol <i>O</i>-Acyl Transferase (ACAT) as Hypocholesterolemic Agents. CI-1011:  An Acyl Sulfamate with Unique Cholesterol-Lowering Activity in Animals Fed Noncholesterol-Supplemented Diets

Helen T. Lee, Drago R. Sliskovic, Joseph A. Picard et al. · Journal of Medicinal Chemistry · 1996 · 93 citations

Lipid Disorder, Acyl Sulfamate, Biochemistry +13

Inhibitors of acyl-CoA:cholesterol acyltransferase. 4. A novel series of urea ACAT inhibitors as potential hypocholesterolemic agents

Bharat K. Trivedi, Ann Holmes, Terri L. Stoeber et al. · Journal of Medicinal Chemistry · 1993 · 54 citations · Full text

Inhibitors of Acyl-CoA:Cholesterol<i>O</i>-Acyltransferase. 17. Structure−Activity Relationships of Several Series of Compounds Derived from<i>N</i>-Chlorosulfonyl Isocyanate

Joseph A. Picard, Patrick O’Brien, Drago R. Sliskovic et al. · Journal of Medicinal Chemistry · 1996 · 50 citations · Full text

Biosynthesis, Engineering, Acidic Proton +13

Intramolecular capture of Pummerer rearrangement intermediates. 3. Interrupted Pummerer rearrangement: capture of tricoordinate sulfur species generated under Pummerer rearrangement conditions

Dallas K. Bates, R. Thomas Winters, Joseph A. Picard · The Journal of Organic Chemistry · 1992 · 49 citations