Paraskevi Kokkala

Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses

Efthalia Zervoudi, Emmanuel Saridakis, James R. Birtley et al. · Proceedings of the National Academy of Sciences · 2013 · 125 citations · Full text

Optimization and Structure–Activity Relationships of Phosphinic Pseudotripeptide Inhibitors of Aminopeptidases That Generate Antigenic Peptides

Paraskevi Kokkala, Anastasia Mpakali, François‐Xavier Mauvais et al. · Journal of Medicinal Chemistry · 2016 · 62 citations · Full text

Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1

Petros Giastas, Anastasia Mpakali, Athanasios Papakyriakou et al. · Proceedings of the National Academy of Sciences · 2019 · 60 citations · Full text

Protein Secretion, Protein Assembly, Peptide Engineering +19

Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

Despoina Koumantou, Eilon Barnea, Adrian Martín‐Esteban et al. · Cancer Immunology Immunotherapy · 2019 · 55 citations · Full text

Protein Function, Signal Transduction, Potent Inhibitor +6

Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and Processing

Anastasia Mpakali, Emmanuel Saridakis, Karl Harlos et al. · The Journal of Immunology · 2015 · 50 citations