Despoina Koumantou

Effects of polymorphic variation on the mechanism of Endoplasmic Reticulum Aminopeptidase 1

Athanasios Stamogiannos, Despoina Koumantou, Athanasios Papakyriakou et al. · Molecular Immunology · 2015 · 70 citations

Protein Function, Biochemistry, Protein Folding +9

Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

Despoina Koumantou, Eilon Barnea, Adrian Martín‐Esteban et al. · Cancer Immunology Immunotherapy · 2019 · 55 citations · Full text

Protein Function, Signal Transduction, Potent Inhibitor +6

Autoimmune Disease-Associated Variants of Extracellular Endoplasmic Reticulum Aminopeptidase 1 Induce Altered Innate Immune Responses by Human Immune Cells

Yasser A. Aldhamen, Yuliya Pepelyayeva, David P. W. Rastall et al. · Journal of Innate Immunity · 2015 · 46 citations · Full text

Erap1 Polymorphic Variants, Inflammatory Lung Disease, Innate Immune System +28

IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses

Irini Evnouchidou, Pascal Chappert, Samira Benadda et al. · Nature Communications · 2020 · 44 citations · Full text

Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation

John Liddle, Jonathan P. Hutchinson, Semra Kitchen et al. · Journal of Medicinal Chemistry · 2020 · 43 citations · Full text