David P. W. Rastall

Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens

Sergey S. Seregin, David P. W. Rastall, Irini Evnouchidou et al. · Autoimmunity · 2013 · 63 citations · Full text

Immunology, Immune Regulation, Pathology +28

Autoimmune Disease-Associated Variants of Extracellular Endoplasmic Reticulum Aminopeptidase 1 Induce Altered Innate Immune Responses by Human Immune Cells

Yasser A. Aldhamen, Yuliya Pepelyayeva, David P. W. Rastall et al. · Journal of Innate Immunity · 2015 · 46 citations · Full text

Erap1 Polymorphic Variants, Inflammatory Lung Disease, Innate Immune System +28

Endoplasmic Reticulum Aminopeptidase-1 Functions Regulate Key Aspects of the Innate Immune Response

Yasser A. Aldhamen, Sergey S. Seregin, David P. W. Rastall et al. · PLoS ONE · 2013 · 34 citations · Full text

Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice

Sergey S. Seregin, Yasser A. Aldhamen, David P. W. Rastall et al. · Vaccine · 2011 · 33 citations

Vaccination, Mucosal Vaccination, Cross-protection +9

ERAP1 deficient mice have reduced Type 1 regulatory T cells and develop skeletal and intestinal features of Ankylosing Spondylitis

Yuliya Pepelyayeva, David P. W. Rastall, Yasser A. Aldhamen et al. · Scientific Reports · 2018 · 33 citations · Full text