Christopher J. Draper-Joyce

Structure of the adenosine-bound human adenosine A1 receptor–Gi complex

Christopher J. Draper-Joyce, Maryam Khoshouei, David M. Thal et al. · Nature · 2018 · 337 citations

Life Sciences, Biochemistry, Pharmacology +10

Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia

Christopher J. Draper-Joyce, Rebecca F. Bhola, Jinan Wang et al. · Nature · 2021 · 158 citations · Full text

Medicine, Biochemistry, Pharmacology +14

Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination

Yi-Lynn Liang, Peishen Zhao, Christopher J. Draper-Joyce et al. · ACS Pharmacology & Translational Science · 2018 · 156 citations · Full text

Life Sciences, Biochemistry, Biology +17

A new mechanism of allostery in a G protein–coupled receptor dimer

J. Robert Lane, Prashant Donthamsetti, Jeremy Shonberg et al. · Nature Chemical Biology · 2014 · 122 citations · Full text

Medicine, Biochemistry, Pharmacology +16

Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D ₂ Receptor Through Fragmentation of a Bitopic Ligand

Shailesh N. Mistry, Jeremy Shonberg, Christopher J. Draper-Joyce et al. · Journal of Medicinal Chemistry · 2015 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17