Prashant Donthamsetti

The role of kinetic context in apparent biased agonism at GPCRs

Carmen Klein Herenbrink, David A. Sykes, Prashant Donthamsetti et al. · Nature Communications · 2016 · 330 citations · Full text

Molecular Determinants of Selectivity and Efficacy at the Dopamine D3 Receptor

Amy Hauck Newman, Thijs Beuming, Ashwini K. Banala et al. · Journal of Medicinal Chemistry · 2012 · 176 citations · Full text

Drug Target, Neurotransmitter, Psychopharmacology +18

A new mechanism of allostery in a G protein–coupled receptor dimer

J. Robert Lane, Prashant Donthamsetti, Jeremy Shonberg et al. · Nature Chemical Biology · 2014 · 120 citations · Full text

Receptor Dimer, Molecular Pharmacology, Molecular Physiology +8

New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion

Zachary J. Farino, Travis J. Morgenstern, Antonella Maffei et al. · Molecular Psychiatry · 2019 · 88 citations · Full text

D3 Receptors, Insulin Management, Physiology +8

Optical control of sphingosine-1-phosphate formation and function

Johannes Morstein, Rose Z. Hill, A. Novák et al. · Nature Chemical Biology · 2019 · 87 citations · Full text

Optical Materials, Engineering, Optical Properties +6