Petra Goelzer

Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), A Potent and Selective Cyclin-Dependent Kinase Inhibitor with Significant in Vivo Antitumor Activity

Xin‐Jie Chu, Wanda DePinto, David Bartkovitz et al. · Journal of Medicinal Chemistry · 2006 · 116 citations · Full text

Drug Target, Pharmacotherapy, Cell Cycle +17

<i>In vitro</i> and <i>in vivo</i> activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials

Wanda DePinto, Xin‐Jie Chu, Xuefeng Yin et al. · Molecular Cancer Therapeutics · 2006 · 102 citations · Full text

Molecular Pharmacology, Tumor Biology, Cell Cycle Block +15

The Influence of Glutathione and Detoxifying Enzymes on DNA Damage Induced by 2-Alkenals in Primary Rat Hepatocytes and Human Lymphoblastoid Cells

Gerhard Eisenbrand, Joachim Schuhmacher, Petra Goelzer · Chemical Research in Toxicology · 1995 · 58 citations

The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of CH4987655 in Healthy Volunteers: Target Suppression Using a Biomarker

Lucy Lee, Huifeng Niu, Ruediger Rueger et al. · Clinical Cancer Research · 2009 · 41 citations

DNA Adducts from <i>N-</i>Nitrosodiethanolamine and Related β-Oxidized Nitrosamines in Vivo:  ³²P-Postlabeling Methods for Glyoxal- and <i>O</i>⁶-Hydroxyethyldeoxyguanosine Adducts

Richard N. Loeppky, Qiuping Ye, Petra Goelzer et al. · Chemical Research in Toxicology · 2002 · 40 citations

Glycobiology, Dna Analysis, Chemical Biology +18