Lucy Lee

The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of CH4987655 in Healthy Volunteers: Target Suppression Using a Biomarker

Lucy Lee, Huifeng Niu, Ruediger Rueger et al. · Clinical Cancer Research · 2009 · 41 citations

Medicine, Pharmacokinetics, Pharmacology +14

The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of RO5068760, an MEK Inhibitor, in Healthy Volunteers: Assessment of Target Suppression

Lucy Lee, Huifeng Niu, Petra Goelzer et al. · The Journal of Clinical Pharmacology · 2010 · 11 citations

Medicine, Pharmacokinetics, Pharmacology +13

[18 F]FDG-PET imaging is an early non-invasive pharmacodynamic biomarker for a first-in-class dual MEK/Raf inhibitor, RO5126766 (CH5126766), in preclinical xenograft models

Tetyana Tegnebratt, Lucy Lee, Valérie Méresse et al. · EJNMMI Research · 2013 · 10 citations · Full text

Medicine, Oncology, Pharmacology +17