William J. McClellan

Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL

Milan Bruncko, Thorsten Oost, Barbara Belli et al. · Journal of Medicinal Chemistry · 2007 · 294 citations · Full text

Immunology, Pharmacotherapy, Pharmaceutical Chemistry +19

A Small-Molecule Inhibitor of Bcl-XL Potentiates the Activity of Cytotoxic Drugs <i>In vitro</i> and <i>In vivo</i>

Alex R. Shoemaker, Anatol Oleksijew, Joy Bauch et al. · Cancer Research · 2006 · 146 citations

Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo

Michael Wendt, Shen Wang, Aaron Kunzer et al. · Journal of Medicinal Chemistry · 2006 · 130 citations · Full text

Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of <i>N</i>-Phenyl Amide 6-Substitution

Michael Wendt, Todd W. Rockway, Andrew Geyer et al. · Journal of Medicinal Chemistry · 2003 · 66 citations · Full text

Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors

Le Wang, John K. Pratt, Todd Soltwedel et al. · Journal of Medicinal Chemistry · 2017 · 64 citations · Full text