I. Samardjiev

Determination of N-Heterocyclic Carbene (NHC) Steric and Electronic Parameters using the [(NHC)Ir(CO)₂Cl] System

Roy A. Kelly, Hervé Clavier, S. Giudice et al. · Organometallics · 2007 · 588 citations

Natural Sciences, Chemistry, Inorganic Chemistry +16

Discovery of Clinical Candidate 1-{[(2 <i>S</i> ,3 <i>S</i> ,4 <i>S</i> )-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design

Katherine L. Lee, Catherine M. Ambler, David R. Anderson et al. · Journal of Medicinal Chemistry · 2017 · 145 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit

Brian S. Gerstenberger, John D. Trzupek, C. Tallant et al. · Journal of Medicinal Chemistry · 2016 · 110 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Twisted Amide Reduction under Wolff−Kishner Conditions:  Synthesis of a Benzo-1-Aza-Adamantane Derivative

Crystal G. Bashore, I. Samardjiev, Jon Bordner et al. · Journal of the American Chemical Society · 2003 · 67 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

An Asymmetric Synthesis of (2<i>S</i>,5<i>S</i>)-5-Substituted Azepane-2-Carboxylate Derivatives

Donn G. Wishka, Marion Bédard, Katherine E. Brighty et al. · The Journal of Organic Chemistry · 2011 · 17 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10