HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

Georgyi V. Los, Lance P. Encell, Mark G. McDougall, +17

ACS Chemical Biology

EngineeringProtein AnalysisMolecular BiologyProtein TagChemical Biology +19

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

Rachel Deplus, Benjamin Delatte, Marie K. Schwinn, +15

The EMBO Journal

ChromatinSignal TransductionBiochemistryNatural SciencesEpigenetic Change +6

Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation

Omer Gilan, Inmaculada Rioja, Kathy Knezevic, +34

Science

Quantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action

Kristin M. Riching, Sarah D. Mahan, Cesear Corona, +5

ACS Chemical Biology

Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

Satomi Imaide, Kristin M. Riching, Nikolai Makukhin, +14

Nature Chemical Biology

Protein ChemistryProtein FunctionBiochemistryProtein AssemblyProtein Folding +3

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

S. Picaud, O. Fedorov, Angeliki Thanasopoulou, +34

Cancer Research

HaloTag7: A genetically engineered tag that enhances bacterial expression of soluble proteins and improves protein purification

Rachel Friedman Ohana, Lance P. Encell, Kate Zhao, +4

Protein Expression and Purification

EngineeringNatural SciencesMolecular BiologySynthetic BiologyBacterial Expression +7

The TIP60 Complex Is a Conserved Coactivator of HIF1A

Joel I. Perez-Perri, Veronica L. Dengler, K. Audrey Audetat, +8

Cell Reports

Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs

Nan Bai, Kristin M. Riching, Aman Makaju, +12

Journal of Biological Chemistry

Protein AssemblyMolecular BiologyTarget Protein UbiquitinationUbiquitin-proteasome SystemProtein Expression +18

Trypsin/Lys-C protease mix for enhanced protein mass spectrometry analysis

Sergei Saveliev, Mark Bratz, Roman A. Zubarev, +3

Nature Methods

Proteomic TechnologyBiochemistryNatural SciencesMedicineBioanalysis +5