Patrick B. Mullins

Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening

Jeremy S. Disch, Jennifer M. Duffy, Esther C. Y. Lee et al. · Journal of Medicinal Chemistry · 2021 · 71 citations · Full text

Medicine, Medicinal Chemistry, Oncology +16

A New and Useful Method for the Macrocyclization of Linear Peptides

Allyn T. Londregan, Kathleen A. Farley, Chris Limberakis et al. · Organic Letters · 2012 · 52 citations

Pharmacy, Medicinal Chemistry, Drug Design +16

Design of potent inhibitors of human β-secretase. Part 2

John N. Freskos, Yvette M. Fobian, Timothy E. Benson et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 39 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability

Martin Pettersson, Douglas S. Johnson, John M. Humphrey et al. · ACS Medicinal Chemistry Letters · 2015 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators

Martin Pettersson, Douglas S. Johnson, Chakrapani Subramanyam et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11