John N. Freskos

Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease

Daniel P. Becker, Thomas E. Barta, Louis J. Bedell et al. · Journal of Medicinal Chemistry · 2010 · 97 citations · Full text

Spare Mmp-1, Pharmacotherapy, Pharmaceutical Chemistry +17

Synthesis of functionalized hydroxyphthalides and their conversion to 3-cyano-1(3H)-isobenzofuranones. The Diels-Alder reaction of methyl 4,4-diethoxybutynoate and cyclohexadienes

John N. Freskos, Gary W. Morrow, John S. Swenton · The Journal of Organic Chemistry · 1985 · 82 citations

Chemical Engineering, Derivative (Chemistry), Bioorganic Chemistry +13

Multicompartment Polymer Nanostructures with Ratiometric Dual-Emission pH-Sensitivity

Guorong Sun, Honggang Cui, Lily Yun Lin et al. · Journal of the American Chemical Society · 2011 · 79 citations

Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy

Daniel P. Becker, Clara I. Villamil, Thomas E. Barta et al. · Journal of Medicinal Chemistry · 2005 · 64 citations · Full text

Pharmaceutical Science, Breast Oncology, Immunology +23

Hydrophilic Pyrazine Dyes as Exogenous Fluorescent Tracer Agents for Real-Time Point-of-Care Measurement of Glomerular Filtration Rate

Raghavan Rajagopalan, William L. Neumann, Amruta R. Poreddy et al. · Journal of Medicinal Chemistry · 2011 · 49 citations

Pharmaceutical Science, Engineering, Real-time Point-of-care Measurement +19