Randy Hecht

Effects of the <i>obese</i> Gene Product on Body Weight Regulation in <i>ob</i> / <i>ob</i> Mice

Mary Ann Pelleymounter, Mary Jane Cullen, Mary Baker et al. · Science · 1995 · 4K citations

Life Sciences, Biochemistry, Endocrinology +17

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

Jing Xu, David J. Lloyd, Clarence Hale et al. · Diabetes · 2008 · 1.1K citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects

Jing Xu, Shanaka Stanislaus, Narumol Chinookoswong et al. · American Journal of Physiology-Endocrinology and Metabolism · 2009 · 338 citations

Medicine, Endocrinology, Pharmacology +17

FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation

Xinle Wu, Hongfei Ge, Bryan D. Lemon et al. · Journal of Biological Chemistry · 2009 · 180 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes

Randy Hecht, Yuesheng Li, Jeonghoon Sun et al. · PLoS ONE · 2012 · 166 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +16