Mario Niepel

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

Marc Hafner, Mario Niepel, Mirra Chung et al. · Nature Methods · 2016 · 698 citations · Full text

Medicine, Epidemiology Of Cancer, Pharmacology +10

Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

William W. Chen, Birgit Schoeberl, Paul Jasper et al. · Molecular Systems Biology · 2009 · 402 citations · Full text

Mass Action Model, Signal Transduction, Input–output Behavior +11

L1000CDS2: LINCS L1000 characteristic direction signatures search engine

Qiaonan Duan, St. Patrick Reid, Neil R. Clark et al. · npj Systems Biology and Applications · 2016 · 370 citations · Full text

Discovery of Potent and Selective Covalent Inhibitors of JNK

Tinghu Zhang, Francisco Iñesta-Vaquera, Mario Niepel et al. · Chemistry & Biology · 2012 · 351 citations · Full text

Medicinal Chemistry, Medicine, Pharmacology +4

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures

Qiaonan Duan, Corey Flynn, Mario Niepel et al. · Nucleic Acids Research · 2014 · 335 citations · Full text

Genetics, Molecular Biology, Gene Characterization +22