Paul Jasper

Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

William W. Chen, Birgit Schoeberl, Paul Jasper et al. · Molecular Systems Biology · 2009 · 402 citations · Full text

Mass Action Model, Signal Transduction, Input–output Behavior +11

Bridging the gap between in vitro and in vivo: Dose and schedule predictions for the ATR inhibitor AZD6738

Stephen Checkley, Linda MacCallum, James Yates et al. · Scientific Reports · 2015 · 69 citations · Full text

Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 Cells

A. Zur, Tristan S. Maurer, Sook Wah Yee et al. · Drug Metabolism and Disposition · 2015 · 66 citations · Full text

Positive selection of the peripheral B cell repertoire in gut-associated lymphoid tissues

Ki‐Jong Rhee, Paul Jasper, Periannan Sethupathi et al. · The Journal of Experimental Medicine · 2004 · 64 citations · Full text

Impaired SHP2-Mediated Extracellular Signal-Regulated Kinase Activation Contributes to Gefitinib Sensitivity of Lung Cancer Cells with Epidermal Growth Factor Receptor–Activating Mutations

Matthew J. Lazzara, Keara Lane, Richard Chan et al. · Cancer Research · 2010 · 63 citations · Full text