Rupa Shetty

Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors

Hong Lin, Min Wang, Yang W. Zhang et al. · ACS Medicinal Chemistry Letters · 2019 · 63 citations · Full text

Drug Target, Bioorganic Chemistry, Aldo-keto Reductase +16

Synthesis and Pharmacological Evaluation of <i>N</i>-(3-(1<i>H</i>-Indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a Potent Antimitotic Agent

Rupa Shetty, Younghee Lee, Bin Liu et al. · Journal of Medicinal Chemistry · 2010 · 34 citations

Two classes of p38α MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes

Enrique L. Michelotti, Kristofer K. Moffett, Duyan Nguyen et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 32 citations · Full text

Molecular Pharmacology, Drug Target, Biochemistry +11

Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD)

Kristofer K. Moffett, Zenon Konteatis, Duyan Nguyen et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 27 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +9