Jan Neelissen

Discovery of Novel Potent and Highly Selective Glycogen Synthase Kinase-3β (GSK3β) Inhibitors for Alzheimer’s Disease: Design, Synthesis, and Characterization of Pyrazines

Stefan von Berg, Margareta Bergh, Sven Hellberg et al. · Journal of Medicinal Chemistry · 2012 · 145 citations · Full text

Characterization of AZD4694, a novel fluorinated Aβ plaque neuroimaging PET radioligand

Anders Juréus, Britt‐Marie Swahn, Johan Sandell et al. · Journal of Neurochemistry · 2010 · 139 citations

Positron Emission Tomography, Neuroimaging Biomarkers, Neurodegenerative Diseases +14

Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds

Anna-Karin Sohlenius-Sternbeck, Lovisa Afzelius, Peteris Prūsis et al. · Xenobiotica · 2010 · 127 citations

Human Prediction, Drug Compounds, Microsome Cl +16

AZD2184: a radioligand for sensitive detection of β‐amyloid deposits

Allan E. Johnson, Fredrik Jeppsson, Johan Sandell et al. · Journal of Neurochemistry · 2008 · 120 citations

Engineering, Pharmacotherapy, β‐Amyloid Deposits +19

<scp>AZD</scp>1080, a novel <scp>GSK</scp>3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans

Biljana Georgievska, Johan Sandin, James Doherty et al. · Journal of Neurochemistry · 2013 · 116 citations · Full text

Synaptic Plasticity Deficits, Synaptic Transmission, Neurotransmission +26