James Doherty

Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial

Stephen Kanes, Helen Colquhoun, Handan Gunduz‐Bruce et al. · The Lancet · 2017 · 468 citations

Psychiatry, Mood Symptom, Medicine +13

Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studies

Rajesh Krishna, Matt S. Anderson, Arthur Bergman et al. · The Lancet · 2007 · 276 citations

Metabolic Syndrome, Hypertension, Healthy Individuals +10

Altered Histone Acetylation at<i>Glutamate Receptor 2</i>and<i>Brain-Derived Neurotrophic Factor</i>Genes Is an Early Event Triggered by Status Epilepticus

Yunfei Huang, James Doherty, Raymond Dingledine · Journal of Neuroscience · 2002 · 258 citations · Full text

Epigenetic Change, Genetics, Synaptic Transmission +21

The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of<i>N</i>-Methyl-d-Aspartate Receptors

Steven M. Paul, James Doherty, Albert J. Robichaud et al. · Journal of Neuroscience · 2013 · 256 citations · Full text

A Selective Allosteric Potentiator of the M₁Muscarinic Acetylcholine Receptor Increases Activity of Medial Prefrontal Cortical Neurons and Restores Impairments in Reversal Learning

Jana K. Shirey, Ashley E. Brady, Paulianda J. Jones et al. · Journal of Neuroscience · 2009 · 238 citations · Full text