Lovisa Afzelius

State-of-the-art Tools for Computational Site of Metabolism Predictions: Comparative Analysis, Mechanistical Insights, and Future Applications

Lovisa Afzelius, Catrin Hasselgren Arnby, Anders Broo et al. · Drug Metabolism Reviews · 2007 · 140 citations

Medicine, Biochemistry, Pharmacology +17

Predicting Drug Metabolism:  A Site of Metabolism Prediction Tool Applied to the Cytochrome P450 2C9

Ismael Zamora, Lovisa Afzelius, Gabriele Cruciani · Journal of Medicinal Chemistry · 2003 · 137 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds

Anna-Karin Sohlenius-Sternbeck, Lovisa Afzelius, Peteris Prūsis et al. · Xenobiotica · 2010 · 128 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Competitive CYP2C9 Inhibitors: Enzyme Inhibition Studies, Protein Homology Modeling, and Three-Dimensional Quantitative Structure-Activity Relationship Analysis

Lovisa Afzelius, Ismael Zamora, Marianne Ridderström et al. · Molecular Pharmacology · 2001 · 96 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Practical use of the regression offset approach for the prediction of<i>in vivo</i>intrinsic clearance from hepatocytes

Anna-Karin Sohlenius-Sternbeck, Chris Jones, Douglas Ferguson et al. · Xenobiotica · 2012 · 95 citations

Pharmacy, Pharmacokinetics, Pharmacology +17