Douglas Ferguson

On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology

David B. Chou, Viktoras Frismantas, Yuka Milton et al. · Nature Biomedical Engineering · 2020 · 296 citations · Full text

Medicine, Cell Biology, Hematology +15

Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies

Bernard Barlaam, Robert Casella, Justin Cidado et al. · Journal of Medicinal Chemistry · 2020 · 104 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Practical use of the regression offset approach for the prediction of<i>in vivo</i>intrinsic clearance from hepatocytes

Anna-Karin Sohlenius-Sternbeck, Chris Jones, Douglas Ferguson et al. · Xenobiotica · 2012 · 95 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Early Prediction of Polymyxin-Induced Nephrotoxicity With Next-Generation Urinary Kidney Injury Biomarkers

Natalie Keirstead, Matthew P. Wagoner, Patricia Bentley et al. · Toxicological Sciences · 2013 · 88 citations · Full text

Medicine, Pharmacology, Toxicology +16

The Specific Monocarboxylate Transporter (MCT1) Inhibitor, AR-C117977, a Novel Immunosuppressant, Prolongs Allograft Survival in the Mouse

Valquíria Bueno, Isabelle Binet, Ulrich Steger et al. · Transplantation · 2007 · 50 citations

Medicine, Immunology, Pharmacology +17