Holly Brunton

The Immune Microenvironment Confers Resistance to MAPK Pathway Inhibitors through Macrophage-Derived TNFα

Michael P. Smith, Berta Sanchez‐Laorden, Kate O’Brien et al. · Cancer Discovery · 2014 · 209 citations · Full text

Medicine, Immunology, Oncology +17

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer

Stephan B. Dreyer, Rosanna Upstill‐Goddard, Viola Paulus-Hock et al. · Gastroenterology · 2020 · 173 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer

Holly Brunton, Giuseppina Caligiuri, Richard Cunningham et al. · Cell Reports · 2020 · 127 citations · Full text

Medicine, Cancer Biology, Oncology +17

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

Lisa Woodbine, Holly Brunton, Aaron A. Goodarzi et al. · Nucleic Acids Research · 2011 · 125 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage

Nakako Izumi Nakajima, Holly Brunton, Ritsuko Watanabe et al. · PLoS ONE · 2013 · 75 citations · Full text

Medicine, Biophysics, Physics +17