William O. Kline

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Sue C. Bodine, Trevor N. Stitt, Michael Gonzalez et al. · Nature Cell Biology · 2001 · 2.7K citations

Life Sciences, Molecular Biology, Physiology +14

The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors

Trevor N. Stitt, Doreen Drujan, Brian Clarke et al. · Molecular Cell · 2004 · 1.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Conditional Activation of Akt in Adult Skeletal Muscle Induces Rapid Hypertrophy

Ka‐Man Venus Lai, Michael Gonzalez, William Poueymirou et al. · Molecular and Cellular Biology · 2004 · 430 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15

Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

Mark W. Sleeman, Katherine E. Wortley, Ka‐Man Venus Lai et al. · Nature Medicine · 2005 · 249 citations

Life Sciences, Biochemistry, Endocrinology +13

Rapamycin inhibits the growth and muscle-sparing effects of clenbuterol

William O. Kline, Frank J. Panaro, Hayung Yang et al. · Journal of Applied Physiology · 2006 · 176 citations

Life Sciences, Pharmacology, Physiology +13