Isabel Iriepa

Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil–indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

Óscar M. Bautista‐Aguilera, Gerard Esteban, Irene Bolea et al. · European Journal of Medicinal Chemistry · 2014 · 141 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease

Li Wang, Gerard Esteban, Masaki Ojima et al. · European Journal of Medicinal Chemistry · 2014 · 138 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase

Ehab D. AlFadly, Perihan A. Elzahhar, Anna Tramarin et al. · European Journal of Medicinal Chemistry · 2019 · 103 citations · Full text

Life Sciences, Neuroscience, Pharmacology +14

Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H₃R Antagonism for Neurodegenerative Diseases

Óscar M. Bautista‐Aguilera, Stefanie Hagenow, Alejandra Palomino‐Antolín et al. · Angewandte Chemie International Edition · 2017 · 101 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Nitric oxide blocks hKv1.5 channels by S-nitrosylation and by a cyclic GMP-dependent mechanism

Luis M. Vaquero, Ricardo Gómez, Ricardo Caballero et al. · Cardiovascular Research · 2006 · 86 citations · Full text

Medicine, Cardiology, Pharmacology +17