Concepedia

Harry Saville

HS

Statistics

Publications

7

Citations

273

H-Index

7

Active since

2016

Affiliations

Institute of Cancer Research(Current)

Cancer Research UK

Breast Cancer Now

Harry Saville is an author at Institute of Cancer Research specializing in drug discovery, molecular biology, and medicine.

Top concepts

Publications per year

2016–2023

7

Publications

7

The effects of adaptive working memory training and mindfulness meditation training on processing efficiency and worry in high worriers

Jenna Course-Choi, Harry Saville, Nazanin Derakshan · Behaviour Research and Therapy · 2016 · 87 citations

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SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response

Philip Bland, Harry Saville, Patty T. Wai et al. · Nature Genetics · 2023 · 39 citations · Full text

High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers

Simon Anderhub, Grace Wing-Yan Mak, Mark D. Gurden et al. · Molecular Cancer Therapeutics · 2019 · 37 citations

Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4-<i>d</i>]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate <i>N</i><sup>2</sup>-(2-Ethoxy-4-(4-methyl-4<i>H</i>-1,2,4-triazol-3-yl)phenyl)-6-methyl-<i>N</i><sup>8</sup>-neopentylpyrido[3,4-<i>d</i>]pyrimidine-2,8-diamine (BOS172722)

Hannah L. Woodward, Paolo Innocenti, Kwai-Ming J. Cheung et al. · Journal of Medicinal Chemistry · 2018 · 33 citations · Full text

Rapid Discovery of Pyrido[3,4-<i>d</i>]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach

Paolo Innocenti, Hannah L. Woodward, Savade Solanki et al. · Journal of Medicinal Chemistry · 2016 · 32 citations · Full text

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