Mark D. Gurden

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer

Ilirjana Bajrami, Rebecca Marlow, Marieke van de Ven et al. · Cancer Discovery · 2018 · 129 citations · Full text

Structure-Based Design of Orally Bioavailable 1<i>H</i>-Pyrrolo[3,2-<i>c</i>]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1)

Sébastien Naud, Isaac M. Westwood, Amir Faisal et al. · Journal of Medicinal Chemistry · 2013 · 79 citations · Full text

Pharmaceutical Science, Molecular Biology, Mps1 Inhibition +20

Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F

Mark D. Gurden, Andrew J. Holland, Wouter van Zon et al. · Journal of Cell Science · 2010 · 56 citations · Full text

Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosis

Mark D. Gurden, Simon Anderhub, Amir Faisal et al. · Oncotarget · 2016 · 40 citations · Full text

High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers

Simon Anderhub, Grace Wing-Yan Mak, Mark D. Gurden et al. · Molecular Cancer Therapeutics · 2019 · 37 citations