Sophia Y. Lunt

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Dimitrios Anastasiou, Yimin Yu, William J. Israelsen et al. · Nature Chemical Biology · 2012 · 804 citations · Full text

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Sandra Schoors, Ulrike Brüning, Rindert Missiaen et al. · Nature · 2015 · 626 citations · Full text

Angiogenesis, Fatty Acid Carbon, Biochemistry +11

Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation

Sophia Y. Lunt, Vinayak Muralidhar, Aaron M. Hosios et al. · Molecular Cell · 2014 · 274 citations · Full text

Impact Cell Proliferation, Cell Regulation, Biochemistry +11

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

Matteo Rossi, Patricia Altea‐Manzano, Margherita Demicco et al. · Nature · 2022 · 200 citations · Full text

Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism

Paul‐Joseph Aspuria, Sophia Y. Lunt, Leif Väremo et al. · Cancer & Metabolism · 2014 · 181 citations · Full text