Sonia Lamontagne

The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs

Mark Abramovitz, Mohammed Adam, Yves Boie et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2000 · 557 citations · Full text

Life Sciences, Biochemistry, Pharmacology +10

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

Jacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 473 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Discovery of a Potent and Selective Prostaglandin D₂ Receptor Antagonist, [(3<i>R</i>)-4-(4-Chloro- benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[<i>b</i>]indol-3-yl]-acetic Acid (MK-0524)

Claudio F. Sturino, Gary P. O’Neill, Nicolas Lachance et al. · Journal of Medicinal Chemistry · 2007 · 170 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +8

Lysosomotropism of Basic Cathepsin K Inhibitors Contributes to Increased Cellular Potencies against Off-Target Cathepsins and Reduced Functional Selectivity

Jean‐Pierre Falgueyret, Sylvie Desmarais, Renata M. Oballa et al. · Journal of Medicinal Chemistry · 2005 · 153 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Structure–activity relationship of cinnamic acylsulfonamide analogues on the human EP3 prostanoid receptor

Hélène Jûteau, Yves Gareau, Marc Labelle et al. · Bioorganic & Medicinal Chemistry · 2001 · 121 citations

Medicine, Medicinal Chemistry, Pharmacology +10