A. C. REID

Synthesis and Activity of a Novel Series of 3-Biarylquinuclidine Squalene Synthase Inhibitors

George R. Brown, David S. Clarke, Alan J. Foubister et al. · Journal of Medicinal Chemistry · 1996 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Novel optimised quinuclidine squalene synthase inhibitors

George R. Brown, Alan J. Foubister, S Freeman et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 15 citations

Pharmacy, Chemistry, Medicinal Chemistry +7

The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases

Dearg S. Brown, John G. Cumming, Paul A. Bethel et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 11 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Quinoline, 1,5-naphthyridine and pyridine derivatives as potent, nonpeptidic angiotensin II receptor antagonists

C. Allott, Robert H. Bradbury, Michael Robert Dennis et al. · Bioorganic & Medicinal Chemistry Letters · 1993 · 11 citations

Medicine, Medicinal Chemistry, Pharmacology +11

N-Methyl-2-[4-(2-methylpropyl)phenyl]-3-(3-methoxy-5-methylpyrazin-2-ylsulfamoyl)benzamide; one of a class of novel benzenesulphonamides which are orally-active, ETA-selective endothelin antagonists

Andrew Mortlock, Colin Bath, Roger J. Butlin et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 10 citations

Medicine, Medicinal Chemistry, Pharmacology +7