David E. MacCallum

Seliciclib (CYC202, R-Roscovitine) Induces Cell Death in Multiple Myeloma Cells by Inhibition of RNA Polymerase II–Dependent Transcription and Down-regulation of Mcl-1

David E. MacCallum, Jean Melville, Sheelagh Frame et al. · Cancer Research · 2005 · 284 citations · Full text

Apoptosis, Cell Death, Cell Cycle +16

The p53 response to ionising radiation in adult and developing murine tissues.

David E. MacCallum, Ted R. Hupp, C A Midgley et al. · PubMed · 1996 · 202 citations

ISWI Remodeling Complexes in<i>Xenopus</i>Egg Extracts: Identification as Major Chromosomal Components that Are Regulated by INCENP-aurora B

David E. MacCallum, Ana Losada, Ryûji Kobayashi et al. · Molecular Biology of the Cell · 2002 · 135 citations · Full text

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival

Azra Alvi, Belinda Austen, Victoria Weston et al. · Blood · 2005 · 133 citations

The location of pKi67 in the outer dense fibrillary compartment of the nucleolus points to a role in ribosome biogenesis during the cell division cycle

David E. MacCallum, Peter A. Hall · The Journal of Pathology · 2000 · 119 citations

Molecular Biology, Cell Death, Cytoskeleton +22