Belinda Austen

Mutation Status of the Residual <i>ATM</i> Allele Is an Important Determinant of the Cellular Response to Chemotherapy and Survival in Patients With Chronic Lymphocytic Leukemia Containing an 11q Deletion

Belinda Austen, Anna Skowrońska, Claire Baker et al. · Journal of Clinical Oncology · 2007 · 243 citations · Full text

Life Sciences, Genetics, Oncology +12

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers

Chris Pepper, Thet Thet Lin, Guy Pratt et al. · Blood · 2008 · 241 citations · Full text

Medicine, Molecular Biology, Oncology +9

Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B-CLL

Belinda Austen, Judith E. Powell, Azra Alvi et al. · Blood · 2005 · 233 citations · Full text

Medicine, Molecular Genetics, Oncology +11

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival

Azra Alvi, Belinda Austen, Victoria Weston et al. · Blood · 2005 · 133 citations

Life Sciences, Cell Biology, Molecular Biology +16

Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses

Tatjana Stanković, Debbie Cronin, Grant S. Stewart et al. · Blood · 2003 · 99 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17