Victoria Weston

Aberrant Interactions of Transcriptional Repressor Proteins with the Huntington's Disease Gene Product, Huntingtin

Jonathan M. Boutell, P. Thomas, J. W. Neal et al. · Human Molecular Genetics · 1999 · 317 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo

Victoria Weston, Ceri Oldreive, Anna Skowrońska et al. · Blood · 2010 · 305 citations · Full text

Medicine, Oncology, Pharmacology +9

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival

Azra Alvi, Belinda Austen, Victoria Weston et al. · Blood · 2005 · 133 citations

Life Sciences, Cell Biology, Molecular Biology +16

Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses

Tatjana Stanković, Debbie Cronin, Grant S. Stewart et al. · Blood · 2003 · 99 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia

David Da Costa, Angelo Agathanggelou, Tracey Perry et al. · Blood Cancer Journal · 2013 · 85 citations · Full text

Medicine, Molecular Biology, Oncology +17