Takahisa Kanekiyo

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

Zhen Zhao, Abhay P. Sagare, Qingyi Ma et al. · Nature Neuroscience · 2015 · 395 citations · Full text

Neurodegenerative Diseases, Central Role, Brain-immune Interaction +6

APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids

Jing Zhao, Yuan Fu, Yu Yamazaki et al. · Nature Communications · 2020 · 352 citations · Full text

Neuronal Clearance of Amyloid-β by Endocytic Receptor LRP1

Takahisa Kanekiyo, John R. Cirrito, Chia‐Chen Liu et al. · Journal of Neuroscience · 2013 · 269 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +15

APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease

Katherine L. Youmans, Leon M. Tai, Evelyn Nwabuisi‐Heath et al. · Journal of Biological Chemistry · 2012 · 264 citations · Full text

Neurodegenerative Diseases, Developmental Biology, Alzheimer's Disease +9

Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition

Chia‐Chen Liu, Jin Hu, Na Zhao et al. · Journal of Neuroscience · 2017 · 251 citations · Full text