ApoE4 Accelerates Early Seeding of Amyloid Pathology

Chia‐Chen Liu, Na Zhao, Yuan Fu, +4

Neuron

Alzheimer's DiseaseDegenerative PathologyProtein MisfoldingAmyloid PathologyMedicine +1

Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes

Na Zhao, Chia‐Chen Liu, Alexandra J. Van Ingelgom, +6

Neuron

Metabolic SyndromeSignal TransductionMolecular PhysiologyBiochemistryDiabetes +6

Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition

Chia‐Chen Liu, Jin Hu, Na Zhao, +6

Journal of Neuroscience

Alzheimer’s Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways

Na Zhao, Yingxue Ren, Yu Yamazaki, +28

Neuron

Neurodegenerative DiseasesMolecular NeuroscienceAgingAlzheimer's DiseaseApoe Genotype +9

The level of galactose-deficient IgA1 in the sera of patients with IgA nephropathy is associated with disease progression

Na Zhao, Ping Hou, Jicheng Lv, +6

Kidney International

Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer’s disease

Chia‐Chen Liu, Na Zhao, Yu Yamaguchi, +4

Science Translational Medicine

Anticancer Peptidylarginine Deiminase (PAD) Inhibitors Regulate the Autophagy Flux and the Mammalian Target of Rapamycin Complex 1 Activity

Yuji Wang, Pingxin Li, Shu Wang, +10

Journal of Biological Chemistry

APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid

Na Zhao, Olivia N. Attrebi, Yingxue Ren, +21

Science Translational Medicine

TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

Manling Xie, Yong Liu, Shunyi Zhao, +14

Nature Neuroscience

InflammationNeurodegenerative DiseasesMedicineImmunologyMicroglial Neuroprotection +9

Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function

Chia‐Chen Liu, Jing Zhao, Yuan Fu, +37

Nature Neuroscience

Neurodegenerative DiseasesAlzheimer's DiseaseVascular DementiaDegenerative PathologyNeurology +7