Takanori Komada

Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure

Naoya Yamada, Tadayoshi Karasawa, Hiroaki Kimura et al. · Cell Death and Disease · 2020 · 341 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Iron overload as a risk factor for hepatic ischemia-reperfusion injury in liver transplantation: Potential role of ferroptosis

Naoya Yamada, Tadayoshi Karasawa, Taiichi Wakiya et al. · American Journal of Transplantation · 2020 · 278 citations · Full text

Medicine, Biochemistry, Inflammation +14

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

Jaye M. Platnich, Hyunjae Chung, Arthur Lau et al. · Cell Reports · 2018 · 189 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells

Ariunaa Sampilvanjil, Tadayoshi Karasawa, Naoya Yamada et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2020 · 166 citations

Life Sciences, Cell Biology, Pharmacology +10

Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD

Takanori Komada, Hyunjae Chung, Arthur Lau et al. · Journal of the American Society of Nephrology · 2018 · 152 citations · Full text

Veterinary Medicine, Immunology, Pathology +17