Jaye M. Platnich

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

Jaye M. Platnich, Hyunjae Chung, Arthur Lau et al. · Cell Reports · 2018 · 189 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD

Takanori Komada, Hyunjae Chung, Arthur Lau et al. · Journal of the American Society of Nephrology · 2018 · 152 citations · Full text

Veterinary Medicine, Immunology, Pathology +17

NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis

Hyunjae Chung, Akosua Vilaysane, Arthur Lau et al. · Cell Death and Differentiation · 2016 · 113 citations

Life Sciences, Cell Biology, Molecular Biology +15

Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury

Arthur Lau, Hyunjae Chung, Takanori Komada et al. · Journal of Clinical Investigation · 2018 · 109 citations · Full text

Life Sciences, Immunology, Pathobiology +17

The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition

Paul Lemire, Susan J. Robertson, Heather Maughan et al. · Cell Reports · 2017 · 98 citations · Full text

Life Sciences, Immunology, Microbiology +17