Concepedia

Lars Dittus

LD

Statistics

Publications

5

Citations

446

H-Index

5

Active since

2016

Affiliations

GlaxoSmithKline (Germany)(Current)

GlaxoSmithKline (United States)

University of Strathclyde

South College

Lars Dittus is an author at GlaxoSmithKline (Germany) specializing in pharmacology, drug discovery, and medicinal chemistry.

Publications per year

2016–2019

5

Publications

5

PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase Is Inhibited by Covalent Binding

Christopher P. Tinworth, Hannah Lithgow, Lars Dittus et al. · ACS Chemical Biology · 2019 · 182 citations

, , +17

Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition

Samuel E. Dalton, Lars Dittus, Daniel A. Thomas et al. · Journal of the American Chemical Society · 2017 · 114 citations

, , +17

A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level

Anna Rutkowska, Douglas W. Thomson, Johanna Vappiani et al. · ACS Chemical Biology · 2016 · 87 citations

, , +15

Differential Kinobeads Profiling for Target Identification of Irreversible Kinase Inhibitors

Lars Dittus, Thilo Werner, Marcel Muelbaier et al. · ACS Chemical Biology · 2017 · 33 citations

, , +17

Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines

Douglas W. Thomson, Anne J. Wagner, Marcus Bantscheff et al. · Journal of Medicinal Chemistry · 2017 · 30 citations · Full text

, , +16

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