Douglas W. Thomson

Identifying drug targets in tissues and whole blood with thermal-shift profiling

Jessica Perrin, Thilo Werner, Nils Kurzawa et al. · Nature Biotechnology · 2020 · 187 citations

Drug Target, Hit Identification, Medicine +12

Highly Efficient Reduction of Unactivated Aryl and Alkyl Iodides by a Ground‐State Neutral Organic Electron Donor

John A. Murphy, Tanweer A. Khan, Shengze Zhou et al. · Angewandte Chemie International Edition · 2005 · 160 citations

Organic Charge-transfer Compound, Organic Material Chemistry, Chemical Engineering +14

The Generation of Aryl Anions by Double Electron Transfer to Aryl Iodides from a Neutral Ground‐State Organic Super‐Electron Donor

John A. Murphy, Shengze Zhou, Douglas W. Thomson et al. · Angewandte Chemie International Edition · 2007 · 136 citations

Organic Charge-transfer Compound, Chemical Engineering, Cross-coupling Reaction +14

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor

Douglas W. Thomson, Daniel Poeckel, Nico Zinn et al. · ACS Medicinal Chemistry Letters · 2019 · 87 citations · Full text

Immune Regulation, Immunology, Immunologic Mechanism +24

A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level

Anna Rutkowska, Douglas W. Thomson, Johanna Vappiani et al. · ACS Chemical Biology · 2016 · 84 citations